The effect of vanadate on aqueous humor dynamics in cynomolgus monkeys.
نویسندگان
چکیده
Topical administration of 1% vanadate in a formulation designed to enhance penetration lowered intraocular pressure in monkeys' eyes. The decrease in intraocular pressure was associated with significant decreases in aqueous humor flow. Tonographic outflow facility was unaltered by topical vanadate.
منابع مشابه
The Effect of Vanadate on Aqueous Humor Dynomics in Cynomolgus Monkeys
3. Eakins K: The effect of intravitreous injections of norepinephrine, epinephrine and isoproterenol on the intraocular pressure and aqueous humor dynamics of rabbit eyes. J Pharmacol Exp Ther 140:79, 1963. 4. Gaasterland D, Kupfer C, Ross K, and Gabelnick HL: Studies of aqueous humor dynamics in man. III. Measurements in young normal subjects using norepinephrine and isoproterenol. Invest Opht...
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'1-albumin was used to determine the rate of bulk outflow from the anterior chamber in one eye and I-albumin was used in the other. In 16 eyes at a spontaneous intraocular pressure of 8.0 ± 0.7 mm. Hg, uveoscleral flow was 0.63 ± 0.08 nL per minute and flow by fast, vascular routes was 0.53 ± 0.07 fiL per minute. When the intraocular pressure was lowered to 2 or 4 mm. Hg by letting aqueous flow...
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ورودعنوان ژورنال:
- Investigative ophthalmology & visual science
دوره 25 3 شماره
صفحات -
تاریخ انتشار 1984